We have developed a tumour growth model based on data from clinical tumour growth rates in Malmö, Sweden. The aim is to simulate a continuation of the Malmö Breast Tomosynthesis Screening Trial, by setting up a virtual clinical trial (VCT). We have evaluated our tumour growth model and shown that there is no significant difference between clinical and estimated growth rates. This implies that the proposed tumour growth model has close agreement with clinical result, which supports its potential use in VCTs of breast imaging.

Currently, we are aiming at refining our simulations and the tumour growth model, to enable simulations of realistic breast models that can be used for predicting clinical outcomes. This will involve further research regarding clinical tumour growth and other tumour characteristics. We will also continue with observer studies on our simulated mammograms, as we progress with our simulations.

With this project we hope to add an additional tool to clinical research regarding breast cancer and breast cancer screening.