LUCI- Lund University breast Cancer Imaging group – is an interdisciplinary research group with members covering expert areas in diagnostic radiology, radiography, medical radiation physics and engineering.
Cancer imaging is a growing field with screening programs for secondary prevention through early detection and advances in therapeutics as key drivers. Since primary prevention strategies are lacking for many types of cancers, imaging has a pivotal role in early detection, diagnosis and treatment response evaluation.
The current scope of our research group embraces a wide spectrum of clinical cancer imaging research. Our field ranges from the epidemiological perspective to the perspective of an individual and person-centered care, through clinical trials, patient-reported outcome studies and qualitative studies, and towards optimization and exploration of established and future imaging techniques. At present our main focus is breast imaging, however we also run projects including other types of cancer such as prostate, colorectal cancer, lung cancer and metastatic disease including imaging modalities such as MRI and PET/CT.
The research group is composed of a diversity of professions ensuring translational and interdisciplinary work. Radiologists, radiographers, medical physicists, engineers, and experts in statistics together form the core in the different projects. In addition, important national and international collaborations are established in the fields of e.g. surgery, medical oncology, pathology, oncogenetics and health economy as well as with the technical faculty, LTH.
Our clinical trials are performed in close and fruitful collaboration with Unilabs AB, the provider of breast imaging diagnostics in Region Skåne as well as the Department of Imaging and Functional Medicine at Skåne University Hospital.
Background and history
Malmö has a strong tradition of preventive medicine projects and our research group has a long-standing experience especially in mammography screening for breast cancer. Professor Bertil Hood, responsible for the Malmö Preventive Project, was instrumental through the initiation of the idea of a large mammography trial, inspired by the HIP-study in New York, USA during the 1960’s. Dr Ingvar Andersson, radiologist and associate professor of radiology, took the lead and paved the way with pioneering randomized, controlled mammography screening trials in Malmö in the 1970 and 80’s together with the late Lars Janzon, professor of epidemiology. In addition to the preventive approaches with large cohorts, a fruitful collaboration was also established with the medical radiation physics group, at that time led by Professor Sören Mattsson. This successful partnership has rendered numerous publications regarding dose optimization, image quality and technical development within the field of breast imaging. The successors, Sophia Zackrisson, radiologist and professor of radiology and Anders Tingberg, associate professor of medical radiation physics now carry the tradition with the recent population-based screening trial investigating 3D mammography (breast tomosynthesis) as a screening tool (The Malmö Breast Tomosynthesis Screening Trial, MBTST). The research groups Diagnostic Radiology and Medical Radiation physics at the Department of Translational Medicine in Malmö hence continue the close collaboration through Sophia Zackrisson and Lars E Olsson, professor of medical radiation physics and Anders Tingberg and co-workers with a clear focus on improved clinically cancer imaging.
Professor Sophia Zackrisson
sophia [dot] zackrisson [at] med [dot] lu [dot] se
Department of translational medicine,
Carl Bertil Laurells gata 9
205 02 Malmö