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Portrait of Anders Tingberg. Photo

Anders Tingberg

Associate professor

Portrait of Anders Tingberg. Photo

Using simple mathematical functions to simulate pathological structures--input for digital mammography clinical trial.

Author

  • Mark Ruschin
  • Anders Tingberg
  • M Båth
  • Anna Grahn
  • M Håkansson
  • Bengt Hemdal
  • I Andersson

Summary, in English

In this study a set of structures has been simulated to represent a range of clinically relevant breast cancer mammographic lesions including solid tumours and microcalcifications. All structures have been created using simple random-based mathematical functions and have been inserted into a subset of digital mammography images at appropriate contrast levels into various regions of the breast, including dense fibroglandular and adipose tissue. These structures and their appearance in these clinical images were evaluated in terms of how realistic they looked. They will be used as the input to a large-scale clinical trial designed to examine the effect of significant dose reduction in digital mammography by comparing the detectability of such structures in images acquired at full and quarter automatic exposure control (AEC) dose level and in images with simulated noise levels in between

Department/s

  • Medical Radiation Physics, Malmö

Publishing year

2005

Language

English

Pages

424-431

Publication/Series

Radiation Protection Dosimetry

Volume

114

Issue

1-3

Document type

Journal article

Publisher

Oxford University Press

Topic

  • Radiology, Nuclear Medicine and Medical Imaging

Keywords

  • adipose tissue
  • contrast level
  • fibroglandular tissue
  • random-based mathematical function
  • microcalcification
  • solid tumour
  • breast cancer mammographic lesion
  • pathological structure
  • digital mammography
  • noise level
  • automatic exposure control dose level
  • dose reduction
  • image acquisition

Conference name

Second Malmo Conference on Medical X-Ray Imaging

Conference date

2004-04-25

Conference place

Malmo, Sweden

Status

Published

Research group

  • Medical Radiation Physics, Malmö

ISBN/ISSN/Other

  • ISSN: 1742-3406