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Portrait of Sophia Zackrisson. Photo

Sophia Zackrisson

Research group manager, Principal investigator, Professor, MD, PhD

Portrait of Sophia Zackrisson. Photo

Breast cancer diagnosis using extended-wavelength diffuse reflectance spectroscopy : comparing tumor subgroups

Author

  • N. Chaudhry
  • A. Kinos
  • M. Ruchkina
  • A. Zabiliūtė-Karaliūnė
  • E. Bukartė
  • S. Kröll
  • S. Zackrisson
  • N. Reistad

Editor

  • Maryellen L. Giger
  • Heather M. Whitney
  • Karen Drukker
  • Hui Li

Summary, in English

Optical imaging utilize light to analyze biological tissues in detail, non-invasively and without harmful radiation. Examples include ultrasound optical tomography and photoacoustic imaging; both use a limited number of wavelengths. Diffuse reflectance spectroscopy, another optical technique, covers a continuous wavelength range, but without generating an image. This study focuses on extended-wavelength DRS (450-1550 nm) to compare healthy breast tissue with different subgroups of breast cancer. Analysis of 13 breast specimens with invasive ductal or lobular carcinoma reveals distinct optical profiles in tumor subgroups compared to healthy tissue. However, absorption and scattering patterns are similar among the tumor subgroups.

Department/s

  • LUCC: Lund University Cancer Centre
  • Radiology Diagnostics, Malmö
  • Department of Translational Medicine
  • LU Profile Area: Light and Materials
  • LTH Profile Area: Photon Science and Technology
  • Atomic Physics
  • LTH Profile Area: Nanoscience and Semiconductor Technology
  • NanoLund: Centre for Nanoscience
  • LTH Profile Area: Engineering Health
  • EpiHealth: Epidemiology for Health
  • Lund Laser Centre, LLC

Publishing year

2024

Language

English

Publication/Series

Proceedings of SPIE - The International Society for Optical Engineering

Document type

Paper in conference proceeding

Publisher

SPIE

Topic

  • Radiology and Medical Imaging
  • Atom and Molecular Physics and Optics

Keywords

  • absorption
  • Breast cancer
  • diffuse reflectance spectroscopy
  • extended wavelength
  • scattering
  • SDG 3 - Good Health and Well-being

Conference name

17th International Workshop on Breast Imaging, IWBI 2024

Conference date

2024-06-09 - 2024-06-12

Conference place

Chicago, United States

Status

Published

Report number

13174

Research group

  • Radiology Diagnostics, Malmö

ISBN/ISSN/Other

  • ISBN: 9781510680203
  • ISSN: 1996-756X
  • ISSN: 0277-786X