Sophia Zackrisson
Research group manager, Principal investigator, Professor, MD
Effectiveness of Population-Based Service Screening With Mammography for Women Ages 40 to 49 Years Evaluation of the Swedish Mammography Screening in Young Women (SCRY) Cohort
Author
Summary, in English
BACKGROUND: The effectiveness of mammography screening for women ages 40 to 49 years still is questioned, and few studies of the effectiveness of service screening for this age group have been conducted. METHODS: Breast cancer mortality was compared between women who were invited to service screening at ages 40 to 49 years (study group) and women in the same age group who were not invited during 1986 to 2005 (control group). Together, these women comprise the Mammography Screening of Young Women (SCRY) cohort, which includes all Swedish counties. A prescreening period was defined to facilitate a comparison of mortality in the absence of screening. The outcome measure was refined mortality, ie, breast cancer death for women who were diagnosed during follow-up at ages 40 to 49 years. Relative risks (RRs) with 95% confidence intervals (Os) were estimated. RESULTS: There was no significant difference in breast cancer mortality during the prescreening period. During the study period, there were 803 breast cancer deaths in the study group (7.3 million person-years) and 1238 breast cancer deaths in the control group (8.8 million person-years). The average follow-up was 16 years. The estimated RR for women who were invited to screening was 0.74 (95% Cl, 0.66-0.83), and the RR for women who attended screening was 0.71 (95% CI, 0.620.80). CONCLUSIONS: In this comprehensive study, mammography screening for women ages 40 to 49 years was efficient for reducing breast cancer mortality. Cancer 2011;117:714-22. (C) 2010 American Cancer Society.
Department/s
- Radiology Diagnostics, Malmö
Publishing year
2011
Language
English
Pages
714-722
Publication/Series
Cancer
Volume
117
Issue
4
Document type
Journal article
Publisher
John Wiley & Sons Inc.
Topic
- Cancer and Oncology
Keywords
- mammography
- screening
- breast cancer
- mortality
Status
Published
Research group
- Radiology Diagnostics, Malmö
ISBN/ISSN/Other
- ISSN: 1097-0142