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Portrait of Sophia Zackrisson. Photo

Sophia Zackrisson

Research group manager, Principal investigator, Professor, MD

Portrait of Sophia Zackrisson. Photo

Breast cancer detection in digital breast tomosynthesis and digital mammography - A side-by-side review of discrepant cases.

Author

  • Kristina Lång
  • Ingvar Andersson
  • Sophia Zackrisson

Summary, in English

Objective: To analyse discrepant breast cancer detection in digital breast tomosynthesis (DBT) and digital mammography (DM). Methods: From a previous detection study comparing DBT and DM, 26 discrepant cases were extracted, 19 detected by DBT only and 7 by DM only. An expert panel of 3 radiologists reviewed these cases and documented level of discrepancy, lesion visibility, radiographic pattern, lesion conspicuity and assessed the reason for non-detection. Differences between groups were tested using the Wilcoxon Rank Sum test, the Kruskal-Wallis test and visual grading characteristics. Results: The proportion of lesion periphery in fatty tissue was statistically significantly larger, and there were significantly more spiculated masses in DBT compared to DM in the DBT Only group (p=0.018; p=0.015). The main reasons for missing a lesion were poor lesion visibility when using DM and interpretative error when using DBT. Conclusion: Lesion visualization is superior with DBT, particularly of spiculated tumours. A major reason for non-detection in DBT seems to be interpretative error, which may be due to lack of experience.

Department/s

  • Radiology Diagnostics, Malmö
  • BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation

Publishing year

2014

Language

English

Publication/Series

British Journal of Radiology

Volume

87

Issue

1040

Document type

Journal article review

Publisher

British Institute of Radiology

Topic

  • Radiology, Nuclear Medicine and Medical Imaging

Status

Published

Research group

  • Radiology Diagnostics, Malmö

ISBN/ISSN/Other

  • ISSN: 1748-880X