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Portrait of Predrag Bakic. Photo

Predrag Bakic

Associate Professor

Portrait of Predrag Bakic. Photo

Mammogram registration : A phantom-based evaluation of compressed breast thickness variation effects

Author

  • Frédéric J.P. Richard
  • Predrag R. Bakić
  • Andrew D.A. Maidment

Summary, in English

The temporal comparison of mammograms is complex; a wide variety of factors can cause changes in image appearance. Mammogram registration is proposed as a method to reduce the effects of these changes and potentially to emphasize genuine alterations in breast tissue. Evaluation of such registration techniques is difficult since ground truth regarding breast deformations is not available in clinical mammograms. In this paper, we propose a systematic approach to evaluate sensitivity of registration methods to various types of changes in mammograms using synthetic breast images with known deformations. As a first step, images of the same simulated breasts with various amounts of simulated physical compression have been used to evaluate a previously described nonrigid mammogram registration technique. Registration performance is measured by calculating the average displacement error over a set of evaluation points identified in mammogram pairs. Applying appropriate thickness compensation and using a preferred order of the registered images, we obtained an average displacement error of 1.6 mm for mammograms with compression differences of 1-3 cm. The proposed methodology is applicable to analysis of other sources of mammogram differences and can be extended to the registration of multimodality breast data.

Publishing year

2006-02

Language

English

Pages

188-197

Publication/Series

IEEE Transactions on Medical Imaging

Volume

25

Issue

2

Document type

Journal article

Publisher

IEEE - Institute of Electrical and Electronics Engineers Inc.

Topic

  • Medical Engineering
  • Radiology, Nuclear Medicine and Medical Imaging

Keywords

  • Breast compression
  • Evaluation
  • Finite elements
  • Image registration
  • Mammogram synthesis
  • Mammography
  • Multi-grid optimization
  • Partial differential equations
  • Tissue modeling

Status

Published

ISBN/ISSN/Other

  • ISSN: 0278-0062