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Portrait of Predrag Bakic. Photo

Predrag Bakic

Associate Professor

Portrait of Predrag Bakic. Photo

Evaluation of a flat fielding method for simultaneous DBT and MI acquisition

Author

  • Predrag R. Bakic
  • Magnus Dustler
  • Kristen C. Lau
  • Andrew D.A. Maidment
  • Sophia Zackrisson
  • Anders Tingberg

Editor

  • Hilde Bosmans
  • Nicholas Marshall
  • Chantal Van Ongeval

Summary, in English

We are developing a prototype system for simultaneous digital breast tomosynthesis (DBT) and mechanical imaging (MI). MI maps the local pressure distribution during clinical exams, to distinguish breast abnormalities from the normal tissue. Both DBT alone, and MI when combined with digital mammography, have demonstrated the ability to reduce false positives; however, the benefit of combining DBT with MI has not been investigated. A practical limitation in simultaneous DBT and MI is the presence of the MI sensor in DBT images. Metallic elements of the sensor generate noticeable artifacts, which may interfere with clinical analysis. Previously, we shown that the sensor artifacts can be reduced by flat fielding, which combines projections of the sensor acquired with and without the breast. In this paper we evaluate the flat fielding by assessing artifact reduction and visibility of breast abnormalities. Images of a physical anthropomorphic breast phantom were acquired using a clinical wide-angle DBT system. Visual evaluation was performed by experienced medical physicists. Image quality descriptors were calculated in images with and without flat fielding. To evaluate the visibility of abnormalities we estimated the full width at half maximum (FWHM) for calcifications modeled in the phantom. Our preliminary results suggest a substantial reduction of artifacts by flat fielding (on average 83%). Few noticeable artifacts remain near the breast edge, in the reconstructed image with the sensor in focus. We observed a 17% reduction in the FWHM. Future work would include a detailed assessment, and method optimization using virtual trials as a design aid.

Department/s

  • LUCC: Lund University Cancer Centre
  • Radiology Diagnostics, Malmö
  • Medical Radiation Physics, Malmö
  • EpiHealth: Epidemiology for Health

Publishing year

2020

Language

English

Publication/Series

Proceedings of SPIE - The International Society for Optical Engineering

Volume

11513

Document type

Conference paper

Publisher

SPIE

Topic

  • Cancer and Oncology

Keywords

  • Artifact reduction
  • Digital breast tomosynthesis
  • Flat fielding
  • Image quality evaluation
  • Mechanical imaging
  • Multimodality breast imaging

Conference name

15th International Workshop on Breast Imaging, IWBI 2020

Conference date

2020-05-25 - 2020-05-27

Conference place

Leuven, Belgium

Status

Published

Project

  • Simultaneous Digital Breast Tomosynthesis and Mechanical Imaging

Research group

  • Radiology Diagnostics, Malmö
  • Medical Radiation Physics, Malmö

ISBN/ISSN/Other

  • ISSN: 0277-786X
  • ISSN: 1996-756X
  • ISBN: 9781510638310