Simulation of ultrasound optical tomography (UOT) for characterizing breast tumors

Summary, in English

The capabilities of ultrasound optical tomography (UOT) is investigated through Monte Carlo simulations on realistic breast tissue phantoms constructed using the OpenVCT platform. This work indicates that UOT is a method capable of distinguishing malignant tumor tissue from benign glandular tissue deep inside the breast, despite the natural variations of adipose and glandular compartments within a breast or between breasts with different volume breast densities.

• Author: Adam Kinos; David Hill; Magnus Dustler; Sophia Zackrisson; Lars Rippe; Predrag R. Bakic; Johannes Swartling; Stefan Kröll
• Editor: Valery V. Tuchin; Walter C. Blondel; Zeev Zalevsky
• Department/s: LU Profile Area: Light and Materials; LTH Profile Area: Photon Science and Technology; Atomic Physics; LTH Profile Area: Nanoscience and Semiconductor Technology; LTH Profile Area: Engineering Health; NanoLund: Centre for Nanoscience; LUCC: Lund University Cancer Centre; Radiology Diagnostics, Malmö; Medical Radiation Physics, Malmö; EpiHealth: Epidemiology for Health
• Publishing year: 2024
• Language: English
• Publication/Series: Proceedings of SPIE - The International Society for Optical Engineering
• Volume: 13010
• Links: http://dx.doi.org/10.1117/12.3024090
• Document type: Conference paper
• Publisher: SPIE
• Topic: Radiology, Nuclear Medicine and Medical Imaging; Physical Sciences
• Keywords: breast tumors; Monte Carlo simulations; Ultrasound optical tomography; VCT computational tissue phantoms
• Conference name: Tissue Optics and Photonics III 2024
• Conference date: 2024-04-09 - 2024-04-11
• Conference place: Strasbourg, France
• Status: Published
• Research group: Radiology Diagnostics, Malmö; Medical Radiation Physics, Malmö
• ISBN/ISSN/Other: ISSN: 1996-756X; ISSN: 0277-786X; ISBN: 9781510673380