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Portrait of Anders Tingberg. Photo

Anders Tingberg

Associate professor

Portrait of Anders Tingberg. Photo

Masses detection in breast tomosynthesis and digital mammography: a model observer study

Author

  • Cyril Castella
  • Mark Ruschin
  • Miguel P Eckstein
  • K Kinkel
  • Francis R Verdun
  • Anders Tingberg
  • Francois O Bochud

Summary, in English

In this study, we adapt and apply model observers within the framework of realistic detection tasks in breast tomosynthesis (BT). We use images consisting of realistic masses digitally embedded in real patient anatomical backgrounds, and we adapt specific model observers that have been previously applied to digital mammography (DM). We design alternative forced-choice experiments (AFC) studies for DM and BT tasks in the signal known exactly but variable (SKEV) framework. We compare performance of various linear model observers (non-prewhitening matched filter with an eye filter, and several channelized Hotelling observers (CHO) against human. A good agreement in performance between human and model observers can be obtained when an appropriate internal noise level is adopted. Models achieve the same detection performance across BT and DM with about three times less projected signal intensity in BT than in DM (humans: 3.8), due to the anatomical noise reduction in BT. We suggest that, in the future, model observers can potentially be used as an objective tool for automating the optimization of BT acquisition parameters or reconstruction algorithms, or narrowing a wide span of possible parameter combinations, without requiring human observers studies.

Department/s

  • Medical Radiation Physics, Malmö

Publishing year

2009

Language

English

Publication/Series

[Host publication title missing]

Volume

7263

Document type

Conference paper

Publisher

SPIE

Topic

  • Radiology, Nuclear Medicine and Medical Imaging

Conference name

SPIE Medical Imaging, 2009

Conference date

2009-02-07 - 2009-02-12

Conference place

Orlando, FL, United States

Status

Published

Research group

  • Medical Radiation Physics, Malmö